Cargando…

Establishment of stable cell lines in which the HBV genome replicates episomally for evaluation of antivirals

INTRODUCTION: Due to the increasing resistance to nucleot(s)ide analogs in patients with chronic hepatitis B, development of new antiviral drugs to eradicate hepatitis B virus is still urgently needed. MATERIAL AND METHODS: To date, most studies on evaluating anti-HBV drugs have been performed using...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Suofeng, Li, Yuan, Liu, Bowei, Zhang, Bingyong, Han, Shuangyin, Li, Xiuling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Termedia Publishing House 2018
Materias:	Basic Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069427/ https://www.ncbi.nlm.nih.gov/pubmed/32190152 http://dx.doi.org/10.5114/aoms.2018.79712

Ejemplares similares

A comprehensive genome-wide profiling comparison between HBV and HCV infected hepatocellular carcinoma
por: Sun, Suofeng, et al.
Publicado: (2019)

A novel circular RNA circ-LRIG3 facilitates the malignant progression of hepatocellular carcinoma by modulating the EZH2/STAT3 signaling
por: Sun, Suofeng, et al.
Publicado: (2020)

Knockdown of lncRNA ABHD11-AS1 Suppresses the Tumorigenesis of Pancreatic Cancer via Sponging miR-1231
por: Liu, Bowei, et al.
Publicado: (2020)

Downregulation of miR-486-5p Enhances the Anti-Tumor Effect of 5-Fluorouracil on Pancreatic Cancer Cells
por: Wang, Wei, et al.
Publicado: (2020)

Insulin-like growth factor-1 attenuates oxidative stress-induced hepatocyte premature senescence in liver fibrogenesis via regulating nuclear p53–progerin interaction
por: Luo, Xiaoying, et al.
Publicado: (2019)

A Role for MRE11, NBS1, and Recombination Junctions in Replication and Stable Maintenance of EBV Episomes
por: Dheekollu, Jayaraju, et al.
Publicado: (2007)

Episomal and chromosomal DNA replication and recombination in Entamoeba histolytica
por: Bhattacharya, Sudha
Publicado: (2023)

Episomal HBV persistence within transcribed host nuclear chromatin compartments involves HBx
por: Hensel, Kai O., et al.
Publicado: (2018)

Free episomal and integrated HBV DNA in HBsAg-negative patients with intrahepatic cholangiocarcinoma
por: Pollicino, Teresa, et al.
Publicado: (2019)

Sirtuin 1 ameliorates defenestration in hepatic sinusoidal endothelial cells during liver fibrosis via inhibiting stress‐induced premature senescence
por: Luo, Xiaoying, et al.
Publicado: (2021)

Stable S/MAR-based episomal vectors are regulated at the chromatin level
por: Tessadori, Federico, et al.
Publicado: (2010)

Proteomic Analysis of Human Esophageal Cancer Using Tandem Mass Tag Quantifications
por: Sun, Suofeng, et al.
Publicado: (2020)

Construction of a replication-competent hepatitis B virus vector carrying secreted luciferase transgene and establishment of new hepatitis B virus replication and expression cell lines
por: Ruan, Jie, et al.
Publicado: (2019)

Plasticity of DNA Replication Initiation in Epstein-Barr Virus Episomes
por: Norio, Paolo, et al.
Publicado: (2004)

Bacterial episomes and plasmids;
Publicado: (1969)

The butterfly effect in viral infection: From a host DNA single nucleotide change to HBV episome steadiness
por: Kim, Elena S., et al.
Publicado: (2019)

Stable transformation of an episomal protein-tagging shuttle vector in the piscine diplomonad Spironucleus vortens
por: Dawson, Scott C, et al.
Publicado: (2008)

Novel protein kinase C phosphorylated kinase inhibitor-matrine suppresses replication of hepatitis B virus via modulating the mitogen-activated protein kinase signal
por: Zhou, Shen, et al.
Publicado: (2022)

Epigallocatechin-3-gallate opposes HBV-induced incomplete autophagy by enhancing lysosomal acidification, which is unfavorable for HBV replication
por: Zhong, L, et al.
Publicado: (2015)

G-quadruplex-interacting compounds alter latent DNA replication and episomal persistence of KSHV
por: Madireddy, Advaitha, et al.
Publicado: (2016)

Shortened nuclear matrix attachment regions are sufficient for replication and maintenance of episomes in mammalian cells
por: Wang, Xiao-Yin, et al.
Publicado: (2019)

The SMC5/6 complex: An emerging antiviral restriction factor that can silence episomal DNA
por: Irwan, Ishak D., et al.
Publicado: (2023)

Association of HBV DNA replication with antiviral treatment outcomes in the patients with early-stage HBV-related hepatocellular carcinoma undergoing curative resection
por: Chen, Jian-Lin, et al.
Publicado: (2016)

ENO3 promoted the progression of NASH by negatively regulating ferroptosis via elevation of GPX4 expression and lipid accumulation
por: Lu, Di, et al.
Publicado: (2021)

Topoisomerase Inhibitors Increase Episomal DNA Expression by Inducing the Integration of Episomal DNA in Hepatic Cells
por: Gómez-Moreno, Andoni, et al.
Publicado: (2023)

The First Human Vulvar Intraepithelial Neoplasia Cell Line with Naturally Infected Episomal HPV18 Genome
por: Wu, Ming, et al.
Publicado: (2022)

Semi-stable Production of Bovine IL-4 and GM-CSF in The Mammalian Episomal Expression System
por: Blanco, Federico Carlos, et al.
Publicado: (2021)

Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes
por: Lucifora, Julie, et al.
Publicado: (2018)

Ectopic Expression of AID in a Non-B Cell Line Triggers A∶T and G:C Point Mutations in Non-Replicating Episomal Vectors
por: Jovanic, Tihana, et al.
Publicado: (2008)

Establishment, functional and genetic characterization of three novel patient-derived rectal cancer cell lines
por: Gock, Michael, et al.
Publicado: (2018)

Establishment and characterization of a new human ampullary carcinoma cell line, DPC-X1
por: Xu, Hao, et al.
Publicado: (2023)

Transpositionally active episomal hAT elements
por: O'Brochta, David A, et al.
Publicado: (2009)

Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line
por: Gock, Michael, et al.
Publicado: (2018)

Characterization of Episomal Replication of Bovine Papillomavirus Type 1 DNA in Long-Term Virion-Infected Saccharomyces Cerevisiae Culture
por: Tu, Quanmei, et al.
Publicado: (2021)

Pimobendan Inhibits HBV Transcription and Replication by Suppressing HBV Promoters Activity
por: Yuan, Si-Yu, et al.
Publicado: (2022)

Strategies to identify and edit improvements in synthetic genome segments episomally
por: Rudolph, Alexandra, et al.
Publicado: (2023)

Designer diatom episomes delivered by bacterial conjugation
por: Karas, Bogumil J., et al.
Publicado: (2015)

Topological implications of DNA tumor viral episomes
por: Kim, Eui Tae, et al.
Publicado: (2022)

Generation of Induced Pluripotent Stem Cells from Lymphoblastoid Cell Lines by Electroporation of Episomal Vectors
por: Kim, Myunghyun, et al.
Publicado: (2022)

Advances in HBV infection and replication systems in vitro
por: Xu, Ruirui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_nbicmadvjseftqjf585ga6g25e