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Implications for IV posaconazole dosing in the era of obesity

BACKGROUND: The prevalence of obesity has shown a dramatic increase over recent decades. Obesity is associated with underdosing of antimicrobial drugs for prophylaxis and treatment. Posaconazole is a broad-spectrum triazole antifungal drug licensed for prophylaxis and treatment of invasive fungal in...

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Detalles Bibliográficos
Autores principales:	Wasmann, Roeland E, Smit, Cornelis, van Donselaar, Marieke H, van Dongen, Eric P A, Wiezer, René M J, Verweij, Paul E, Burger, David M, Knibbe, Catherijne A J, Brüggemann, Roger J M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069473/ https://www.ncbi.nlm.nih.gov/pubmed/31971567 http://dx.doi.org/10.1093/jac/dkz546

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