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Madurella mycetomatis, the main causative agent of eumycetoma, is highly susceptible to olorofim
OBJECTIVES: Eumycetoma is currently treated with a combination of itraconazole therapy and surgery, with limited success. Recently, olorofim, the lead candidate of the orotomides, a novel class of antifungal agents, entered a Phase II trial for the treatment of invasive fungal infections. Here we de...
Autores principales: | Lim, Wilson, Eadie, Kimberly, Konings, Mickey, Rijnders, Bart, Fahal, Ahmed H, Oliver, Jason D, Birch, Mike, Verbon, Annelies, van de Sande, Wendy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069493/ https://www.ncbi.nlm.nih.gov/pubmed/31904836 http://dx.doi.org/10.1093/jac/dkz529 |
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