Readily accessible sp(3)-rich cyclic hydrazine frameworks exploiting nitrogen fluxionality

Increased molecular complexity correlates with improved chances of success in the drug development process. Here, a strategy for the creation of sp(3)-rich, non-planar heterocyclic scaffolds suitable for drug discovery is described that obviates the need to generate multiple stereogenic centers with...

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Detalles Bibliográficos
Autores principales: Dean, Conor, Rajkumar, Sundaram, Roesner, Stefan, Carson, Nessa, Clarkson, Guy J., Wills, Martin, Jones, Matthew, Shipman, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069508/
https://www.ncbi.nlm.nih.gov/pubmed/32206282
http://dx.doi.org/10.1039/c9sc04849a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069508/
https://www.ncbi.nlm.nih.gov/pubmed/32206282
http://dx.doi.org/10.1039/c9sc04849a

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