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Readily accessible sp(3)-rich cyclic hydrazine frameworks exploiting nitrogen fluxionality
Increased molecular complexity correlates with improved chances of success in the drug development process. Here, a strategy for the creation of sp(3)-rich, non-planar heterocyclic scaffolds suitable for drug discovery is described that obviates the need to generate multiple stereogenic centers with...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069508/ https://www.ncbi.nlm.nih.gov/pubmed/32206282 http://dx.doi.org/10.1039/c9sc04849a |