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Impact of reperfusion with blood venting on liver transplantation outcomes; a prospective case-control study
AIM: This study aimed to evaluate the impact of two different reperfusion techniques on outcomes of LT patients. BACKGROUND: Post-reperfusion syndrome (PRS) during liver transplantation (LT) remains a serious issue for both the surgeon and anesthetist. METHODS: In this prospective study, all liver t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shaheed Beheshti University of Medical Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069539/ https://www.ncbi.nlm.nih.gov/pubmed/32190225 |
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author | Fakhar, Nasir Chavoshi Khamneh, Abdolhamid Najafi, Atabac Sharifi, Ali Hyder, Zeeshan Salimi, Javad |
author_facet | Fakhar, Nasir Chavoshi Khamneh, Abdolhamid Najafi, Atabac Sharifi, Ali Hyder, Zeeshan Salimi, Javad |
author_sort | Fakhar, Nasir |
collection | PubMed |
description | AIM: This study aimed to evaluate the impact of two different reperfusion techniques on outcomes of LT patients. BACKGROUND: Post-reperfusion syndrome (PRS) during liver transplantation (LT) remains a serious issue for both the surgeon and anesthetist. METHODS: In this prospective study, all liver transplant recipients referred to the liver transplantation department of Imam Khomeini Hospital, Tehran, Iran, from January 2016 to June 2017 were enrolled in the study and were divided into two groups of vented (reperfusion with 300cc blood venting) and non-vented (reperfusion without blood venting) cases. Then, 30-minute intraoperative hemodynamic and biochemical changes, as well as 2-month complications and 6-month mortality, were compared between the groups. RESULTS: 57 LT cases (31 vented and 26 non-vented) were studied (50.9% female). The two groups had a similar age (p = 0.107), sex (p = 0.885), MELD score (p = 0.61), donor warm ischemic time (p = 0.85), recipient warm ischemic time (p = 0.36), cold ischemic time (p = 0.99), comorbid disease (p = 0.502), and etiology of end-stage liver disease (p = 0.281). PRS occurred in 3 (11.5%) patients in the vented group and 4 (12.9%) in the non-vented group (p = 0.69). One (3.8%) patient in the non-vented group and 4 (12.9%) patients in vented group died (p = 0.229). CONCLUSION: Reperfusion with and without blood venting had the same outcome regarding intraoperative hemodynamic and biochemical changes, PRS rate, and postoperative complications, as well as 6-month survival. Thus, it seems that blood venting is not a necessary method for decreasing post-reperfusion complications following LT. |
format | Online Article Text |
id | pubmed-7069539 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Shaheed Beheshti University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-70695392020-03-18 Impact of reperfusion with blood venting on liver transplantation outcomes; a prospective case-control study Fakhar, Nasir Chavoshi Khamneh, Abdolhamid Najafi, Atabac Sharifi, Ali Hyder, Zeeshan Salimi, Javad Gastroenterol Hepatol Bed Bench Original Article AIM: This study aimed to evaluate the impact of two different reperfusion techniques on outcomes of LT patients. BACKGROUND: Post-reperfusion syndrome (PRS) during liver transplantation (LT) remains a serious issue for both the surgeon and anesthetist. METHODS: In this prospective study, all liver transplant recipients referred to the liver transplantation department of Imam Khomeini Hospital, Tehran, Iran, from January 2016 to June 2017 were enrolled in the study and were divided into two groups of vented (reperfusion with 300cc blood venting) and non-vented (reperfusion without blood venting) cases. Then, 30-minute intraoperative hemodynamic and biochemical changes, as well as 2-month complications and 6-month mortality, were compared between the groups. RESULTS: 57 LT cases (31 vented and 26 non-vented) were studied (50.9% female). The two groups had a similar age (p = 0.107), sex (p = 0.885), MELD score (p = 0.61), donor warm ischemic time (p = 0.85), recipient warm ischemic time (p = 0.36), cold ischemic time (p = 0.99), comorbid disease (p = 0.502), and etiology of end-stage liver disease (p = 0.281). PRS occurred in 3 (11.5%) patients in the vented group and 4 (12.9%) in the non-vented group (p = 0.69). One (3.8%) patient in the non-vented group and 4 (12.9%) patients in vented group died (p = 0.229). CONCLUSION: Reperfusion with and without blood venting had the same outcome regarding intraoperative hemodynamic and biochemical changes, PRS rate, and postoperative complications, as well as 6-month survival. Thus, it seems that blood venting is not a necessary method for decreasing post-reperfusion complications following LT. Shaheed Beheshti University of Medical Sciences 2020 /pmc/articles/PMC7069539/ /pubmed/32190225 Text en ©2020 RIGLD, Research Institute for Gastroenterology and Liver Diseases This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Fakhar, Nasir Chavoshi Khamneh, Abdolhamid Najafi, Atabac Sharifi, Ali Hyder, Zeeshan Salimi, Javad Impact of reperfusion with blood venting on liver transplantation outcomes; a prospective case-control study |
title | Impact of reperfusion with blood venting on liver transplantation outcomes; a prospective case-control study |
title_full | Impact of reperfusion with blood venting on liver transplantation outcomes; a prospective case-control study |
title_fullStr | Impact of reperfusion with blood venting on liver transplantation outcomes; a prospective case-control study |
title_full_unstemmed | Impact of reperfusion with blood venting on liver transplantation outcomes; a prospective case-control study |
title_short | Impact of reperfusion with blood venting on liver transplantation outcomes; a prospective case-control study |
title_sort | impact of reperfusion with blood venting on liver transplantation outcomes; a prospective case-control study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069539/ https://www.ncbi.nlm.nih.gov/pubmed/32190225 |
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