Increased von Willebrand Factor Processing in COPD, Reflecting Lung Epithelium Damage, Is Associated with Emphysema, Exacerbations and Elevated Mortality Risk

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation and lung tissue deterioration. Given the high vascularity of the lung, von Willebrand factor (VWF), a central component of wound healing initiation, has previously been assessed in COPD. VWF processing,...

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Detalles Bibliográficos
Autores principales: Langholm, Lasse L, Rønnow, Sarah Rank, Sand, Jannie M B, Leeming, Diana Julie, Tal-Singer, Ruth, Miller, Bruce E, Vestbo, Jørgen, Karsdal, Morten A, Manon-Jensen, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069584/
https://www.ncbi.nlm.nih.gov/pubmed/32210548
http://dx.doi.org/10.2147/COPD.S235673

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