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KLF6 Induces Apoptosis in Human Lens Epithelial Cells Through the ATF4-ATF3-CHOP Axis

BACKGROUND: Many studies have confirmed that high myopia is related to the high prevalence of cataracts, which results from apoptosis of lens epithelial cells (LECs) due to endoplasmic reticulum stress. Krüppel-like factor 6 (KLF6) is a tumor suppressor that is involved in the regulation of cell pro...

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Detalles Bibliográficos
Autores principales:	Tian, Fang, Zhao, Jinzhi, Bu, Shaochong, Teng, He, Yang, Jun, Zhang, Xiaomin, Li, Xiaorong, Dong, Lijie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069589/ https://www.ncbi.nlm.nih.gov/pubmed/32210535 http://dx.doi.org/10.2147/DDDT.S218467

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