Cargando…

KLF6 Induces Apoptosis in Human Lens Epithelial Cells Through the ATF4-ATF3-CHOP Axis

BACKGROUND: Many studies have confirmed that high myopia is related to the high prevalence of cataracts, which results from apoptosis of lens epithelial cells (LECs) due to endoplasmic reticulum stress. Krüppel-like factor 6 (KLF6) is a tumor suppressor that is involved in the regulation of cell pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tian, Fang, Zhao, Jinzhi, Bu, Shaochong, Teng, He, Yang, Jun, Zhang, Xiaomin, Li, Xiaorong, Dong, Lijie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069589/ https://www.ncbi.nlm.nih.gov/pubmed/32210535 http://dx.doi.org/10.2147/DDDT.S218467

Ejemplares similares

Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4‐ATF3‐CHOP axis
por: Tang, Qin, et al.
Publicado: (2019)

Salermide up-regulates death receptor 5 expression through the ATF4-ATF3-CHOP axis and leads to apoptosis in human cancer cells
por: Liu, Guangbo, et al.
Publicado: (2012)

ATF6 Is a Critical Determinant of CHOP Dynamics during the Unfolded Protein Response
por: Yang, Huan, et al.
Publicado: (2020)

Hydrogen peroxide induces nucleus pulposus cell apoptosis by ATF4/CHOP signaling pathway
por: Liu, Yi
Publicado: (2020)

Induction of DR5-Dependent Apoptosis by PGA(2) through ATF4-CHOP Pathway
por: Park, Kyeong-Min, et al.
Publicado: (2022)

ATF2 and ATF7 Are Critical Mediators of Intestinal Epithelial Repair
por: Meijer, Bartolomeus J., et al.
Publicado: (2020)

Flurochloridone Induced Cell Apoptosis via ER Stress and eIF2α-ATF4/ATF6-CHOP-Bim/Bax Signaling Pathways in Mouse TM4 Sertoli Cells
por: Zhang, Fen, et al.
Publicado: (2022)

RGC-specific ATF4 and/or CHOP deletion rescues glaucomatous neurodegeneration and visual function
por: Fang, Fang, et al.
Publicado: (2023)

Fisetin, an Anti-Inflammatory Agent, Overcomes Radioresistance by Activating the PERK-ATF4-CHOP Axis in Liver Cancer
por: Kim, Tae Woo
Publicado: (2023)

Melatonin Protects Against Neuronal Apoptosis via Suppression of the ATF6/CHOP Pathway in a Rat Model of Intracerebral Hemorrhage
por: Xu, Weilin, et al.
Publicado: (2018)

Beam Jitter Studies at ATF and ATF2
por: Pfingstner, Jürgen, et al.
Publicado: (2013)

CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis
por: Teske, Brian F., et al.
Publicado: (2013)

Overlapping and differential functions of ATF6α versus ATF6β in the mouse heart
por: Correll, Robert N., et al.
Publicado: (2019)

ATF4- and CHOP-Dependent Induction of FGF21 through Endoplasmic Reticulum Stress
por: Wan, Xiao-shan, et al.
Publicado: (2014)

Hyperglycemia-triggered ATF6-CHOP pathway aggravates acute inflammatory liver injury by β-catenin signaling
por: Yang, Chao, et al.
Publicado: (2022)

Selection of autophagy or apoptosis in cells exposed to ER-stress depends on ATF4 expression pattern with or without CHOP expression
por: Matsumoto, Hiroki, et al.
Publicado: (2013)

Apoptosis induced by mercuric chloride is associated with upregulation of PERK-ATF4-CHOP pathway in chicken embryonic kidney cells
por: Ma, Yan, et al.
Publicado: (2020)

Genetic Interactions Between Aspergillus fumigatus Basic Leucine Zipper (bZIP) Transcription Factors AtfA, AtfB, AtfC, and AtfD
por: Silva, Lilian Pereira, et al.
Publicado: (2021)

Corrigendum to “ATF4- and CHOP-Dependent Induction of FGF21 through Endoplasmic Reticulum Stress”
por: Wan, Xiao-shan, et al.
Publicado: (2018)

JDP2 is directly regulated by ATF4 and modulates TRAIL sensitivity by suppressing the ATF4–DR5 axis
por: Engler, Máté János, et al.
Publicado: (2020)

A Cytoplasmic Negative Regulator Isoform of ATF7 Impairs ATF7 and ATF2 Phosphorylation and Transcriptional Activity
por: Diring, Jessica, et al.
Publicado: (2011)

Paradoxical roles of ATF6α and ATF6β in modulating disease severity caused by mutations in collagen X
por: Forouhan, M., et al.
Publicado: (2018)

Adaptive Suppression of the ATF4-CHOP Branch of the Unfolded Protein Response by Toll-Like Receptor Signaling
por: Woo, Connie W., et al.
Publicado: (2009)

MIF Inhibition Suppresses Cell Viability and Induces Apoptosis via the ATF4-CHOP Pathway in Mouse Pituitary AtT-20 Cells
por: Wang, Jason, et al.
Publicado: (2021)

Argininosuccinate synthase 1 suppresses tumor progression through activation of PERK/eIF2α/ATF4/CHOP axis in hepatocellular carcinoma
por: Kim, Sanghwa, et al.
Publicado: (2021)

ATP citrate lyase inhibitor triggers endoplasmic reticulum stress to induce hepatocellular carcinoma cell apoptosis via p‐eIF2α/ATF4/CHOP axis
por: Zheng, Yihu, et al.
Publicado: (2021)

ATF linac commissioning
por: Hayano, H
Publicado: (1996)

Timing system of the ATF
por: Naito, T, et al.
Publicado: (1997)

ATF2 COMMISSIONING
por: Seryi, A, et al.
Publicado: (2010)

ATF report 2020
por: Aryshev, Alexander, et al.
Publicado: (2020)

Gremlin-1 Promotes Colorectal Cancer Cell Metastasis by Activating ATF6 and Inhibiting ATF4 Pathways
por: Li, Ruohan, et al.
Publicado: (2022)

Inducible ATF3–NFAT axis aggravates podocyte injury
por: Zhang, Hong, et al.
Publicado: (2017)

Sinulariolide Induced Hepatocellular Carcinoma Apoptosis through Activation of Mitochondrial-Related Apoptotic and PERK/eIF2α/ATF4/CHOP Pathway
por: Chen, Yi-Jen, et al.
Publicado: (2013)

Valdecoxib Protects against Cell Apoptosis Induced by Endoplasmic Reticulum Stress via the Inhibition of PERK-ATF4-CHOP Pathway in Experimental Glaucoma
por: Gao, Zhaolin, et al.
Publicado: (2022)

PERK‐eIF2α‐ATF4‐CHOP Signaling Contributes to TNFα‐Induced Vascular Calcification
por: Masuda, Masashi, et al.
Publicado: (2013)

ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment
por: Xiang, Jiawen, et al.
Publicado: (2023)

miRNA-1283 Regulates the PERK/ATF4 Pathway in Vascular Injury by Targeting ATF4
por: He, Ling, et al.
Publicado: (2016)

Ceapins inhibit ATF6α signaling by selectively preventing transport of ATF6α to the Golgi apparatus during ER stress
por: Gallagher, Ciara M, et al.
Publicado: (2016)

IL-6/STAT3 Induced Neuron Apoptosis in Hypoxia by Downregulating ATF6 Expression
por: Zhou, Simin, et al.
Publicado: (2021)

Plasmin-Induced Lens Epithelial Cells Detachment for the Reduction of Posterior Capsular Opacification
por: Bai, Xiaomei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_a1uuqlrg1qolfuqhdm99p7dsrr