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IDH1 Expression via the R132H Mutation–Specific Antibody in Adrenocortical Neoplasias—Prognostic Impact in Carcinomas

CONTEXT: Mutations to isocitrate dehydrogenase (IDH) appear to play a prognostic or predictive role in several neoplasias. Immunohistochemical staining designed to detect a specific R132H mutation to IDH1 showed expression in the normal adrenal cortex, raising interest to study the potential role of...

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Detalles Bibliográficos
Autores principales: Pennanen, Mirkka, Tynninen, Olli, Kytölä, Soili, Ellonen, Pekka, Mustonen, Harri, Heiskanen, Ilkka, Haglund, Caj, Arola, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069839/
https://www.ncbi.nlm.nih.gov/pubmed/32190803
http://dx.doi.org/10.1210/jendso/bvaa018