Cargando…

Ubiquitin-Specific Protease 22/Silent Information Regulator 1 Axis Plays a Pivotal Role in the Prognosis and 5-Fluorouracil Resistance in Hepatocellular Carcinoma

BACKGROUND: Ubiquitin-specific protease 22 (USP22) is described as a key subunit of the Spt-Ada-Gcn5 acetyl transferase complex, which plays an important role in the prognosis and resistance to chemotherapy drugs in hepatocellular carcinoma (HCC). Silent information regulator 1 (SIRT1) is a member o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wen, Xue, Ling, Sunbin, Wu, Weiqiang, Shan, Qiaonan, Liu, Peng, Wang, Chao, Wei, Xuyong, Ding, Wei, Teng, Xiaodong, Xu, Xiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069902/ https://www.ncbi.nlm.nih.gov/pubmed/31587155 http://dx.doi.org/10.1007/s10620-019-05844-8

Ejemplares similares

Ubiquitin‐specific protease 22 promotes tumorigenesis and progression by an FKBP12/mTORC1/autophagy positive feedback loop in hepatocellular carcinoma
por: Ye, Qianwei, et al.
Publicado: (2023)

Self‐Activated Cascade‐Responsive Sorafenib and USP22 shRNA Co‐Delivery System for Synergetic Hepatocellular Carcinoma Therapy
por: Xu, Shengjun, et al.
Publicado: (2021)

The c-MYC-ABCB5 axis plays a pivotal role in 5-fluorouracil resistance in human colon cancer cells
por: Kugimiya, Naruji, et al.
Publicado: (2015)

Ubiquitin-specific protease 22 promotes lipogenesis contributing to Hepatocellular Carcinoma pathogenesis
por: Xu, Yanyan, et al.
Publicado: (2022)

USP22 mediates the multidrug resistance of hepatocellular carcinoma via the SIRT1/AKT/MRP1 signaling pathway
por: Ling, Sunbin, et al.
Publicado: (2017)

Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1
por: Lin, Zhenghong, et al.
Publicado: (2015)

Targeting the microRNA-21/AP1 axis by 5-fluorouracil and pirarubicin in human hepatocellular carcinoma
por: He, Xiaodong, et al.
Publicado: (2014)

Metformin potentiates the effect of arsenic trioxide suppressing intrahepatic cholangiocarcinoma: roles of p38 MAPK, ERK3, and mTORC1
por: Ling, Sunbin, et al.
Publicado: (2017)

MicroRNA-34a/EGFR axis plays pivotal roles in lung tumorigenesis
por: Li, Y-L, et al.
Publicado: (2017)

Ubiquitin C decrement plays a pivotal role in replicative senescence of bone marrow mesenchymal stromal cells
por: Kim, Jiyeon, et al.
Publicado: (2018)

Role of sevoflurane in myocardial ischemia-reperfusion injury via the ubiquitin-specific protease 22/lysine-specific demethylase 3A axis
por: Song, Shan, et al.
Publicado: (2022)

Prokineticin 2 Plays a Pivotal Role in Psoriasis
por: He, Xiaoqin, et al.
Publicado: (2016)

Metformin reverses multidrug resistance in human hepatocellular carcinoma Bel-7402/5-fluorouracil cells
por: LING, SUNBIN, et al.
Publicado: (2014)

Metformin reverses multidrug resistance in human hepatocellular carcinoma Bel-7402/5-fluorouracil cells
por: Ling, Sunbin, et al.
Publicado: (2022)

Targeting ubiquitin-specific protease 22 suppresses growth and metastasis of anaplastic thyroid carcinoma
por: Zhao, Hua-Dong, et al.
Publicado: (2016)

AKT Axis, miR-21, and RECK Play Pivotal Roles in Dihydroartemisinin Killing Malignant Glioma Cells
por: Shao, Ying-Ying, et al.
Publicado: (2017)

Ubiquitin-specific protease 7 is a drug-able target that promotes hepatocellular carcinoma and chemoresistance
por: Zhang, Wei, et al.
Publicado: (2020)

Next generation sequencing of HIV-1 protease in the PIVOT trial of protease inhibitor monotherapy
por: Dunn, David T., et al.
Publicado: (2018)

Operative ubiquitin-specific protease 22 deubiquitination confers a more invasive phenotype to cholangiocarcinoma
por: Tian, Yu, et al.
Publicado: (2021)

Estrogen-SIRT1 Axis Plays a Pivotal Role in Protecting Arteries Against Menopause-Induced Senescence and Atherosclerosis
por: Sasaki, Yuichi, et al.
Publicado: (2020)

Emerging potential of ubiquitin-specific proteases and ubiquitin-specific proteases inhibitors in breast cancer treatment
por: Huang, Mei-Ling, et al.
Publicado: (2022)

Downregulation of Ubiquitin-Specific Protease 22 Inhibits Proliferation, Invasion, and Epithelial–Mesenchymal Transition in Osteosarcoma Cells
por: Zhang, Dengfeng, et al.
Publicado: (2017)

Comprehensive analysis of ubiquitin‐specific protease 1 reveals its importance in hepatocellular carcinoma
por: Zhao, Yalei, et al.
Publicado: (2020)

Identification and Validation of Ubiquitin-Specific Proteases as a Novel Prognostic Signature for Hepatocellular Carcinoma
por: Ni, Wenkai, et al.
Publicado: (2021)

CXCL12/CXCR4 axis plays pivotal roles in the organ-specific metastasis of pancreatic adenocarcinoma: A clinical study
por: ZHONG, WEIXIA, et al.
Publicado: (2012)

Hevin Plays a Pivotal Role in Corneal Wound Healing
por: Chaurasia, Shyam S., et al.
Publicado: (2013)

Dysregulation of Connexin Expression Plays a Pivotal Role in Psoriasis
por: O’Shaughnessy, Erin M., et al.
Publicado: (2021)

The Pharmaceutical Formulation Plays a Pivotal Role in Hydroxytyrosol Pharmacokinetics
por: Di Renzo, Laura, et al.
Publicado: (2023)

Characterization of the Ubiquitin C-Terminal Hydrolase and Ubiquitin-Specific Protease Families in Rice (Oryza sativa)
por: Wang, Dong-Hui, et al.
Publicado: (2018)

Activated hepatic stellate cells play pivotal roles in hepatocellular carcinoma cell chemoresistance and migration in multicellular tumor spheroids
por: Song, Yeonhwa, et al.
Publicado: (2016)

ELTD1—An Emerging Silent Actor in Cancer Drama Play
por: Sevastre, Ani-Simona, et al.
Publicado: (2021)

Synergistic effect of puerarin and 5-fluorouracil on hepatocellular carcinoma
por: ZENG, YAN-PING, et al.
Publicado: (2014)

Prognostic and clinicopathological significance of ubiquitin-specific protease 22 overexpression in cancers: evidence from a meta-analysis
por: Ao, Ning, et al.
Publicado: (2017)

Ubiquitin-specific protease 22 is critical to in vivo angiogenesis, growth and metastasis of non-small cell lung cancer
por: Zhang, Keqiang, et al.
Publicado: (2019)

High Expression of Ubiquitin-Specific Protease 39 and Its Roles in Prognosis in Patients with Hepatocellular Carcinoma
por: Liao, Yu, et al.
Publicado: (2021)

miR-7/SP1/TP53BP1 axis may play a pivotal role in NSCLC radiosensitivity
por: Guo, Genyan, et al.
Publicado: (2020)

Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system
por: Xu, Daichao, et al.
Publicado: (2015)

Systemic analysis identifying PVT1/DUSP13 axis for microvascular invasion in hepatocellular carcinoma
por: Su, Renyi, et al.
Publicado: (2022)

Substrate specificity of the ubiquitin and Ubl proteases
por: Ronau, Judith A, et al.
Publicado: (2016)

FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21
por: Zhang, Long, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_76m5ef76v925magmo9utqcp4os