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NMR backbone assignment of the Cε4 domain of immunoglobulin E

Immunoglobulin E (IgE) plays a central role in allergic reactions. IgE is a dynamic molecule that is capable of undergoing large conformational changes. X-ray crystal structures of the Fc region of IgE in complex with various ligands have shown that IgE-Fc can exist in extended and various bent conf...

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Detalles Bibliográficos
Autores principales: Benjamin, Stefi V., Creeke, Paul I., Henry, Alistair J., McDonnell, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069932/
https://www.ncbi.nlm.nih.gov/pubmed/32108310
http://dx.doi.org/10.1007/s12104-020-09936-9

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