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NMR backbone assignment of the Cε4 domain of immunoglobulin E
Immunoglobulin E (IgE) plays a central role in allergic reactions. IgE is a dynamic molecule that is capable of undergoing large conformational changes. X-ray crystal structures of the Fc region of IgE in complex with various ligands have shown that IgE-Fc can exist in extended and various bent conf...
Autores principales: | Benjamin, Stefi V., Creeke, Paul I., Henry, Alistair J., McDonnell, James M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069932/ https://www.ncbi.nlm.nih.gov/pubmed/32108310 http://dx.doi.org/10.1007/s12104-020-09936-9 |
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