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Snow Mountain Virus recovery by synthetic human histo-blood group antigens is heavily influenced by matrix effects

Noroviruses are known to bind to histo-blood group antigens (HBGAs) and the specific binding patterns depend on the virus genotype. However, the development of point-of-care diagnostic assays based on this binding has been challenging due to low assay sensitivity. This study utilized a well-defined...

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Detalles Bibliográficos
Autores principales: Kirby, Amy E., Kienast, Yvonne, Aldeco, Milagros, Steele, Molly, Dhawane, Abasaheb N., Liu, Dandan, Cui, Xikai, Das, Amrita, Iyer, Suri, Moe, Christine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069939/
https://www.ncbi.nlm.nih.gov/pubmed/32170122
http://dx.doi.org/10.1038/s41598-020-60639-6