Multi-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity

Transcription factors (TFs) control cell fates by precisely orchestrating gene expression. However, how individual TFs promote transcriptional diversity remains unclear. Here, we use the Hox TF Ultrabithorax (Ubx) as a model to explore how a single TF specifies multiple cell types. Using proximity-d...

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Detalles Bibliográficos
Autores principales: Carnesecchi, Julie, Sigismondo, Gianluca, Domsch, Katrin, Baader, Clara Eva Paula, Rafiee, Mahmoud-Reza, Krijgsveld, Jeroen, Lohmann, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069958/
https://www.ncbi.nlm.nih.gov/pubmed/32170121
http://dx.doi.org/10.1038/s41467-020-15223-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069958/
https://www.ncbi.nlm.nih.gov/pubmed/32170121
http://dx.doi.org/10.1038/s41467-020-15223-x

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