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Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling
Designing and implementing synthetic biological pattern formation remains challenging due to underlying theoretical complexity as well as the difficulty of engineering multicellular networks biochemically. Here, we introduce a cell-in-the-loop approach where living cells interact through in silico s...
Autores principales: | Perkins, Melinda Liu, Benzinger, Dirk, Arcak, Murat, Khammash, Mustafa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069979/ https://www.ncbi.nlm.nih.gov/pubmed/32170129 http://dx.doi.org/10.1038/s41467-020-15166-3 |
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