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A signaling hub of insulin receptor, dystrophin glycoprotein complex and plakoglobin regulates muscle size
Signaling through the insulin receptor governs central physiological functions related to cell growth and metabolism. Here we show by tandem native protein complex purification approach and super-resolution STED microscopy that insulin receptor activity requires association with the fundamental stru...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070008/ https://www.ncbi.nlm.nih.gov/pubmed/32170063 http://dx.doi.org/10.1038/s41467-020-14895-9 |