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Combined reduction in the expression of MCL-1 and BCL-2 reduces organismal size in mice

The intrinsic apoptotic pathway is controlled by the BCL-2 family of proteins, which exhibit either a pro-death or pro-survival function. Gene knockout studies revealed that different pro-survival BCL-2 proteins are critical for the survival of distinct cell types, although overlapping functions amo...

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Detalles Bibliográficos
Autores principales:	Ke, Francine, Lancaster, Graeme I., Grabow, Stephanie, Murphy, Andrew J., Strasser, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070015/ https://www.ncbi.nlm.nih.gov/pubmed/32170090 http://dx.doi.org/10.1038/s41419-020-2376-5

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