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The RNA-binding protein DAZL functions as repressor and activator of mRNA translation during oocyte maturation

Deleted in azoospermia-like (DAZL) is an RNA-binding protein critical for gamete development. In full-grown oocytes, the DAZL protein increases 4-fold during reentry into the meiotic cell cycle. Here, we have investigated the functional significance of this accumulation at a genome-wide level. Deple...

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Detalles Bibliográficos
Autores principales: Yang, Cai-Rong, Rajkovic, Gabriel, Daldello, Enrico Maria, Luong, Xuan G., Chen, Jing, Conti, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070028/
https://www.ncbi.nlm.nih.gov/pubmed/32170089
http://dx.doi.org/10.1038/s41467-020-15209-9