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Podosome formation promotes plasma membrane invagination and integrin-β3 endocytosis on a viscous RGD-membrane

Integrin receptors orchestrate cell adhesion and cytoskeletal reorganization. The endocytic mechanism of integrin-β3 receptor at the podosome remains unclear. Using viscous RGD-membrane as the model system, here we show that the formation of podosome-like adhesion promotes Dab2/clathrin-mediated end...

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Detalles Bibliográficos
Autores principales: Cao, Fakun, Zhou, Yuhuan, Liu, Xiaoting, Yu, Cheng-han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070051/
https://www.ncbi.nlm.nih.gov/pubmed/32170110
http://dx.doi.org/10.1038/s42003-020-0843-2

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