Cargando…
Duration of Elevated Heart Rate Is an Important Predictor of Exercise‐Induced Troponin Elevation
BACKGROUND: The precise mechanisms causing cardiac troponin (cTn) increase after exercise remain to be determined. The aim of this study was to investigate the impact of heart rate (HR) on exercise‐induced cTn increase by using sports watch data from a large bicycle competition. METHODS AND RESULTS:...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070191/ https://www.ncbi.nlm.nih.gov/pubmed/32065043 http://dx.doi.org/10.1161/JAHA.119.014408 |
_version_ | 1783505917923295232 |
---|---|
author | Bjørkavoll‐Bergseth, Magnus Kleiven, Øyunn Auestad, Bjørn Eftestøl, Trygve Oskal, Kay Nygård, Martin Skadberg, Øyvind Aakre, Kristin Moberg Melberg, Tor Gjesdal, Knut Ørn, Stein |
author_facet | Bjørkavoll‐Bergseth, Magnus Kleiven, Øyunn Auestad, Bjørn Eftestøl, Trygve Oskal, Kay Nygård, Martin Skadberg, Øyvind Aakre, Kristin Moberg Melberg, Tor Gjesdal, Knut Ørn, Stein |
author_sort | Bjørkavoll‐Bergseth, Magnus |
collection | PubMed |
description | BACKGROUND: The precise mechanisms causing cardiac troponin (cTn) increase after exercise remain to be determined. The aim of this study was to investigate the impact of heart rate (HR) on exercise‐induced cTn increase by using sports watch data from a large bicycle competition. METHODS AND RESULTS: Participants were recruited from NEEDED (North Sea Race Endurance Exercise Study). All completed a 91‐km recreational mountain bike race (North Sea Race). Clinical status, ECG, blood pressure, and blood samples were obtained 24 hours before and 3 and 24 hours after the race. Participants (n=177) were, on average, 44 years old; 31 (18%) were women. Both cTnI and cTnT increased in all individuals, reaching the highest level (of the 3 time points assessed) at 3 hours after the race (P<0.001). In multiple regression models, the duration of exercise with an HR >150 beats per minute was a significant predictor of both cTnI and cTnT, at both 3 and 24 hours after exercise. Neither mean HR nor mean HR in percentage of maximum HR was a significant predictor of the cTn response at 3 and 24 hours after exercise. CONCLUSIONS: The duration of elevated HR is an important predictor of physiological exercise‐induced cTn elevation. CLINICAL TRIAL REGISTRATION: URL: https://www.clinicaltrials.gov/. Unique identifier: NCT02166216. |
format | Online Article Text |
id | pubmed-7070191 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-70701912020-03-17 Duration of Elevated Heart Rate Is an Important Predictor of Exercise‐Induced Troponin Elevation Bjørkavoll‐Bergseth, Magnus Kleiven, Øyunn Auestad, Bjørn Eftestøl, Trygve Oskal, Kay Nygård, Martin Skadberg, Øyvind Aakre, Kristin Moberg Melberg, Tor Gjesdal, Knut Ørn, Stein J Am Heart Assoc Original Research BACKGROUND: The precise mechanisms causing cardiac troponin (cTn) increase after exercise remain to be determined. The aim of this study was to investigate the impact of heart rate (HR) on exercise‐induced cTn increase by using sports watch data from a large bicycle competition. METHODS AND RESULTS: Participants were recruited from NEEDED (North Sea Race Endurance Exercise Study). All completed a 91‐km recreational mountain bike race (North Sea Race). Clinical status, ECG, blood pressure, and blood samples were obtained 24 hours before and 3 and 24 hours after the race. Participants (n=177) were, on average, 44 years old; 31 (18%) were women. Both cTnI and cTnT increased in all individuals, reaching the highest level (of the 3 time points assessed) at 3 hours after the race (P<0.001). In multiple regression models, the duration of exercise with an HR >150 beats per minute was a significant predictor of both cTnI and cTnT, at both 3 and 24 hours after exercise. Neither mean HR nor mean HR in percentage of maximum HR was a significant predictor of the cTn response at 3 and 24 hours after exercise. CONCLUSIONS: The duration of elevated HR is an important predictor of physiological exercise‐induced cTn elevation. CLINICAL TRIAL REGISTRATION: URL: https://www.clinicaltrials.gov/. Unique identifier: NCT02166216. John Wiley and Sons Inc. 2020-02-17 /pmc/articles/PMC7070191/ /pubmed/32065043 http://dx.doi.org/10.1161/JAHA.119.014408 Text en © 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Research Bjørkavoll‐Bergseth, Magnus Kleiven, Øyunn Auestad, Bjørn Eftestøl, Trygve Oskal, Kay Nygård, Martin Skadberg, Øyvind Aakre, Kristin Moberg Melberg, Tor Gjesdal, Knut Ørn, Stein Duration of Elevated Heart Rate Is an Important Predictor of Exercise‐Induced Troponin Elevation |
title | Duration of Elevated Heart Rate Is an Important Predictor of Exercise‐Induced Troponin Elevation |
title_full | Duration of Elevated Heart Rate Is an Important Predictor of Exercise‐Induced Troponin Elevation |
title_fullStr | Duration of Elevated Heart Rate Is an Important Predictor of Exercise‐Induced Troponin Elevation |
title_full_unstemmed | Duration of Elevated Heart Rate Is an Important Predictor of Exercise‐Induced Troponin Elevation |
title_short | Duration of Elevated Heart Rate Is an Important Predictor of Exercise‐Induced Troponin Elevation |
title_sort | duration of elevated heart rate is an important predictor of exercise‐induced troponin elevation |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070191/ https://www.ncbi.nlm.nih.gov/pubmed/32065043 http://dx.doi.org/10.1161/JAHA.119.014408 |
work_keys_str_mv | AT bjørkavollbergsethmagnus durationofelevatedheartrateisanimportantpredictorofexerciseinducedtroponinelevation AT kleivenøyunn durationofelevatedheartrateisanimportantpredictorofexerciseinducedtroponinelevation AT auestadbjørn durationofelevatedheartrateisanimportantpredictorofexerciseinducedtroponinelevation AT eftestøltrygve durationofelevatedheartrateisanimportantpredictorofexerciseinducedtroponinelevation AT oskalkay durationofelevatedheartrateisanimportantpredictorofexerciseinducedtroponinelevation AT nygardmartin durationofelevatedheartrateisanimportantpredictorofexerciseinducedtroponinelevation AT skadbergøyvind durationofelevatedheartrateisanimportantpredictorofexerciseinducedtroponinelevation AT aakrekristinmoberg durationofelevatedheartrateisanimportantpredictorofexerciseinducedtroponinelevation AT melbergtor durationofelevatedheartrateisanimportantpredictorofexerciseinducedtroponinelevation AT gjesdalknut durationofelevatedheartrateisanimportantpredictorofexerciseinducedtroponinelevation AT ørnstein durationofelevatedheartrateisanimportantpredictorofexerciseinducedtroponinelevation |