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FURIN Expression in Vascular Endothelial Cells Is Modulated by a Coronary Artery Disease–Associated Genetic Variant and Influences Monocyte Transendothelial Migration

BACKGROUND: Genome‐wide association studies have shown an association between the single‐nucleotide polymorphism rs17514846 on chromosome 15q26.1 and coronary artery disease susceptibility. The underlying biological mechanism is, however, not fully understood. rs17514846 is located in the FES Upstre...

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Detalles Bibliográficos
Autores principales:	Yang, Xu, Yang, Wei, McVey, David G., Zhao, Guojun, Hu, Jinfu, Poston, Robin N., Ren, Meixia, Willeit, Karin, Coassin, Stefan, Willeit, Johann, Webb, Thomas R., Samani, Nilesh J., Mayr, Manuel, Kiechl, Stefan, Ye, Shu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070217/ https://www.ncbi.nlm.nih.gov/pubmed/32067586 http://dx.doi.org/10.1161/JAHA.119.014333

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