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Insight into GEBR-32a: Chiral Resolution, Absolute Configuration and Enantiopreference in PDE4D Inhibition

Alzheimer’s disease is the most common type of dementia, affecting millions of people worldwide. One of its main consequences is memory loss, which is related to downstream effectors of cyclic adenosine monophosphate (cAMP). A well-established strategy to avoid cAMP degradation is the inhibition of...

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Detalles Bibliográficos
Autores principales: Cavalloro, Valeria, Russo, Katia, Vasile, Francesca, Pignataro, Luca, Torretta, Archimede, Donini, Stefano, Semrau, Marta S., Storici, Paola, Rossi, Daniela, Rapetti, Federica, Brullo, Chiara, Parisini, Emilio, Bruno, Olga, Collina, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070305/
https://www.ncbi.nlm.nih.gov/pubmed/32093112
http://dx.doi.org/10.3390/molecules25040935