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Synthetic Approaches to a Challenging and Unusual Structure—An Amino-Pyrrolidine Guanine Core

The synthesis of an unreported 2-aminopyrrolidine-1-carboxamidine unit is here described for the first time. This unusual and promising structure was attained through the oxidative decarboxylation of amino acids using the pair of reagents, silver(I)/peroxydisulfate (Ag(I)/S(2)O(8)(2−)) followed by i...

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Detalles Bibliográficos
Autores principales: Rippel, Rafael, Pinheiro, Luís, Lopes, Mónica, Lourenço, Ana, Ferreira, Luísa M., Branco, Paula S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070370/
https://www.ncbi.nlm.nih.gov/pubmed/32059504
http://dx.doi.org/10.3390/molecules25040797

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