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Flow Synthesis of Biologically-Relevant Compound Libraries
Flow chemistry is one of the most prominent enabling technologies that has greatly shaped the way chemists’ approach organic synthesis. Specifically, in drug discovery, the advantages of flow techniques over batch procedures allow the rapid and efficient assembly of compound libraries to be tested f...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070499/ https://www.ncbi.nlm.nih.gov/pubmed/32085549 http://dx.doi.org/10.3390/molecules25040909 |
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author | Luque Navarro, Pilar María Lanari, Daniela |
author_facet | Luque Navarro, Pilar María Lanari, Daniela |
author_sort | Luque Navarro, Pilar María |
collection | PubMed |
description | Flow chemistry is one of the most prominent enabling technologies that has greatly shaped the way chemists’ approach organic synthesis. Specifically, in drug discovery, the advantages of flow techniques over batch procedures allow the rapid and efficient assembly of compound libraries to be tested for biological properties. The aim of the present review is to comment on some representative examples from the last five years of literature that highlight how flow procedures are becoming of increasing importance for the synthesis of biologically-relevant molecules. |
format | Online Article Text |
id | pubmed-7070499 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70704992020-03-19 Flow Synthesis of Biologically-Relevant Compound Libraries Luque Navarro, Pilar María Lanari, Daniela Molecules Review Flow chemistry is one of the most prominent enabling technologies that has greatly shaped the way chemists’ approach organic synthesis. Specifically, in drug discovery, the advantages of flow techniques over batch procedures allow the rapid and efficient assembly of compound libraries to be tested for biological properties. The aim of the present review is to comment on some representative examples from the last five years of literature that highlight how flow procedures are becoming of increasing importance for the synthesis of biologically-relevant molecules. MDPI 2020-02-18 /pmc/articles/PMC7070499/ /pubmed/32085549 http://dx.doi.org/10.3390/molecules25040909 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Luque Navarro, Pilar María Lanari, Daniela Flow Synthesis of Biologically-Relevant Compound Libraries |
title | Flow Synthesis of Biologically-Relevant Compound Libraries |
title_full | Flow Synthesis of Biologically-Relevant Compound Libraries |
title_fullStr | Flow Synthesis of Biologically-Relevant Compound Libraries |
title_full_unstemmed | Flow Synthesis of Biologically-Relevant Compound Libraries |
title_short | Flow Synthesis of Biologically-Relevant Compound Libraries |
title_sort | flow synthesis of biologically-relevant compound libraries |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070499/ https://www.ncbi.nlm.nih.gov/pubmed/32085549 http://dx.doi.org/10.3390/molecules25040909 |
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