Pharmacological Blockade of PPAR Isoforms Increases Conditioned Fear Responding in the Presence of Nociceptive Tone

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors with three isoforms (PPARα, PPARβ/δ, PPARγ) and can regulate pain, anxiety, and cognition. However, their role in conditioned fear and pain-fear interactions has not yet been investigated. Here, we investigated the effects of...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaspar, Jessica C., Okine, Bright N., Llorente-Berzal, Alvaro, Roche, Michelle, Finn, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070536/
https://www.ncbi.nlm.nih.gov/pubmed/32102354
http://dx.doi.org/10.3390/molecules25041007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070536/
https://www.ncbi.nlm.nih.gov/pubmed/32102354
http://dx.doi.org/10.3390/molecules25041007

Ejemplares similares