DEAD-box RNA Helicase DDX3: Functional Properties and Development of DDX3 Inhibitors as Antiviral and Anticancer Drugs

This short review is focused on enzymatic properties of human ATP-dependent RNA helicase DDX3 and the development of antiviral and anticancer drugs targeting cellular helicases. DDX3 belongs to the DEAD-box proteins, a large family of RNA helicases that participate in all aspects of cellular process...

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Detalles Bibliográficos
Autores principales: Kukhanova, Marina K., Karpenko, Inna L., Ivanov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070539/
https://www.ncbi.nlm.nih.gov/pubmed/32102413
http://dx.doi.org/10.3390/molecules25041015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070539/
https://www.ncbi.nlm.nih.gov/pubmed/32102413
http://dx.doi.org/10.3390/molecules25041015

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