Aging and Caloric Restriction Modulate the DNA Methylation Profile of the Ribosomal RNA Locus in Human and Rat Liver

A growing amount of evidence suggests that the downregulation of protein synthesis is an adaptive response during physiological aging, which positively contributes to longevity and can be modulated by nutritional interventions like caloric restriction (CR). The expression of ribosomal RNA (rRNA) is...

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Detalles Bibliográficos
Autores principales: Gensous, Noémie, Ravaioli, Francesco, Pirazzini, Chiara, Gramignoli, Roberto, Ellis, Ewa, Storci, Gianluca, Capri, Miriam, Strom, Stephen, Laconi, Ezio, Franceschi, Claudio, Garagnani, Paolo, Marongiu, Fabio, Bacalini, Maria Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070571/
https://www.ncbi.nlm.nih.gov/pubmed/31973116
http://dx.doi.org/10.3390/nu12020277

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