Efficient Biocatalytic Synthesis of Dihalogenated Purine Nucleoside Analogues Applying Thermodynamic Calculations

The enzymatic synthesis of nucleoside analogues has been shown to be a sustainable and efficient alternative to chemical synthesis routes. In this study, dihalogenated nucleoside analogues were produced by thermostable nucleoside phosphorylases in transglycosylation reactions using uridine or thymid...

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Detalles Bibliográficos
Autores principales: Yehia, Heba, Westarp, Sarah, Röhrs, Viola, Kaspar, Felix, Giessmann, Robert T., Klare, Hendrik F.T., Paulick, Katharina, Neubauer, Peter, Kurreck, Jens, Wagner, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070685/
https://www.ncbi.nlm.nih.gov/pubmed/32093094
http://dx.doi.org/10.3390/molecules25040934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070685/
https://www.ncbi.nlm.nih.gov/pubmed/32093094
http://dx.doi.org/10.3390/molecules25040934

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