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Efficient Biocatalytic Synthesis of Dihalogenated Purine Nucleoside Analogues Applying Thermodynamic Calculations
The enzymatic synthesis of nucleoside analogues has been shown to be a sustainable and efficient alternative to chemical synthesis routes. In this study, dihalogenated nucleoside analogues were produced by thermostable nucleoside phosphorylases in transglycosylation reactions using uridine or thymid...
Autores principales: | Yehia, Heba, Westarp, Sarah, Röhrs, Viola, Kaspar, Felix, Giessmann, Robert T., Klare, Hendrik F.T., Paulick, Katharina, Neubauer, Peter, Kurreck, Jens, Wagner, Anke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070685/ https://www.ncbi.nlm.nih.gov/pubmed/32093094 http://dx.doi.org/10.3390/molecules25040934 |
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