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In Vitro Aging of Human Skin Fibroblasts: Age-Dependent Changes in 4-Hydroxynonenal Metabolism

Evidence suggests that the increased production of free radicals and reactive oxygen species lead to cellular aging. One of the consequences is lipid peroxidation generating reactive aldehydic products, such as 4-hydroxynonenal (HNE) that modify proteins and form adducts with DNA bases. To prevent d...

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Detalles Bibliográficos
Autores principales:	Petkovic, Igor, Bresgen, Nikolaus, Gilardoni, Ettore, Regazzoni, Luca, Uchida, Koji, Aldini, Giancarlo, Siems, Werner, Eckl, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070748/ https://www.ncbi.nlm.nih.gov/pubmed/32053996 http://dx.doi.org/10.3390/antiox9020150

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