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SNP Discrimination by Tolane-Modified Peptide Nucleic Acids: Application for the Detection of Drug Resistance in Pathogens

During the treatment of viral or bacterial infections, it is important to evaluate any resistance to the therapeutic agents used. An amino acid substitution arising from a single base mutation in a particular gene often causes drug resistance in pathogens. Therefore, molecular tools that discriminat...

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Detalles Bibliográficos
Autores principales:	Takagi, Kenji, Hayashi, Tenko, Sawada, Shinjiro, Okazaki, Miku, Hori, Sakiko, Ogata, Katsuya, Kato, Nobuo, Ebara, Yasuhito, Kaihatsu, Kunihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070780/ https://www.ncbi.nlm.nih.gov/pubmed/32053960 http://dx.doi.org/10.3390/molecules25040769

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