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Virtual Screening Approach to Identify High-Affinity Inhibitors of Serum and Glucocorticoid-Regulated Kinase 1 among Bioactive Natural Products: Combined Molecular Docking and Simulation Studies

Serum and glucocorticoid-regulated kinase 1 (SGK1) is a serine/threonine kinase that works under acute transcriptional control by several stimuli, including serum and glucocorticoids. It plays a significant role in the cancer progression and metastasis, as it regulates inflammation, apoptosis, hormo...

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Detalles Bibliográficos
Autores principales:	Mohammad, Taj, Siddiqui, Shiza, Shamsi, Anas, Alajmi, Mohamed F., Hussain, Afzal, Islam, Asimul, Ahmad, Faizan, Hassan, Md. Imtaiyaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070812/ https://www.ncbi.nlm.nih.gov/pubmed/32070031 http://dx.doi.org/10.3390/molecules25040823

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