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Validation of the Spartan RXCYP2C19 Genotyping Assay Utilizing Blood Samples

The antiplatelet agent clopidogrel, a prodrug that requires bioactivation through the cytochrome P450 2C19 (CYP2C19) enzyme, is commonly prescribed post‐percutaneous coronary intervention (PCI). Genetic variation in CYP2C19 contributes to individual variability in clopidogrel response, and can lead...

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Detalles Bibliográficos
Autores principales: Davis, Brittney H., DeFrank, Gina, Limdi, Nita A., Harada, Shuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070822/
https://www.ncbi.nlm.nih.gov/pubmed/31664775
http://dx.doi.org/10.1111/cts.12714