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Hydroxygenkwanin Suppresses Non-Small Cell Lung Cancer Progression by Enhancing EGFR Degradation

Epidermal growth factor receptor (EGFR) is frequently overexpressed and mutated in non-small cell lung cancer (NSCLC), which is the major type of lung cancer. The EGFR tyrosine kinase inhibitors (TKIs) are the approved treatment for patients harboring activating mutations in the EGFR kinase. However...

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Detalles Bibliográficos
Autores principales: Leu, Yann-Lii, Wang, Tong-Hong, Wu, Chih-Ching, Huang, Kuo-Yen, Jiang, Yu-Wen, Hsu, Yi-Chiung, Chen, Chi-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070862/
https://www.ncbi.nlm.nih.gov/pubmed/32093124
http://dx.doi.org/10.3390/molecules25040941