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Candida antarctica Lipase A-Based Enantiorecognition of a Highly Strained 4-Dibenzocyclooctynol (DIBO) Used for PET Imaging

The enantiomers of aromatic 4-dibenzocyclooctynol (DIBO), used for radiolabeling and subsequent conjugation of biomolecules to form radioligands for positron emission tomography (PET), were separated by kinetic resolution using lipase A from Candida antarctica (CAL-A). In optimized conditions, (R)-D...

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Detalles Bibliográficos
Autores principales:	Sirén, Saija, Dahlström, Käthe M., Puttreddy, Rakesh, Rissanen, Kari, Salminen, Tiina A., Scheinin, Mika, Li, Xiang-Guo, Liljeblad, Arto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070869/ https://www.ncbi.nlm.nih.gov/pubmed/32079253 http://dx.doi.org/10.3390/molecules25040879

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