Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues

This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms...

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Detalles Bibliográficos
Autores principales: Ferraz da Costa, Danielly C., Pereira Rangel, Luciana, Martins-Dinis, Mafalda Maria Duarte da Cunha, Ferretti, Giulia Diniz da Silva, Ferreira, Vitor F., Silva, Jerson L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070981/
https://www.ncbi.nlm.nih.gov/pubmed/32085381
http://dx.doi.org/10.3390/molecules25040893
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author Ferraz da Costa, Danielly C.
Pereira Rangel, Luciana
Martins-Dinis, Mafalda Maria Duarte da Cunha
Ferretti, Giulia Diniz da Silva
Ferreira, Vitor F.
Silva, Jerson L.
author_facet Ferraz da Costa, Danielly C.
Pereira Rangel, Luciana
Martins-Dinis, Mafalda Maria Duarte da Cunha
Ferretti, Giulia Diniz da Silva
Ferreira, Vitor F.
Silva, Jerson L.
author_sort Ferraz da Costa, Danielly C.
collection PubMed
description This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms of action and the most recent attempts to improve their bioavailability and potency against different types of cancer.
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spelling pubmed-70709812020-03-19 Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues Ferraz da Costa, Danielly C. Pereira Rangel, Luciana Martins-Dinis, Mafalda Maria Duarte da Cunha Ferretti, Giulia Diniz da Silva Ferreira, Vitor F. Silva, Jerson L. Molecules Review This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms of action and the most recent attempts to improve their bioavailability and potency against different types of cancer. MDPI 2020-02-18 /pmc/articles/PMC7070981/ /pubmed/32085381 http://dx.doi.org/10.3390/molecules25040893 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ferraz da Costa, Danielly C.
Pereira Rangel, Luciana
Martins-Dinis, Mafalda Maria Duarte da Cunha
Ferretti, Giulia Diniz da Silva
Ferreira, Vitor F.
Silva, Jerson L.
Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues
title Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues
title_full Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues
title_fullStr Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues
title_full_unstemmed Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues
title_short Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues
title_sort anticancer potential of resveratrol, β-lapachone and their analogues
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070981/
https://www.ncbi.nlm.nih.gov/pubmed/32085381
http://dx.doi.org/10.3390/molecules25040893
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