Cargando…

Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues

This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ferraz da Costa, Danielly C., Pereira Rangel, Luciana, Martins-Dinis, Mafalda Maria Duarte da Cunha, Ferretti, Giulia Diniz da Silva, Ferreira, Vitor F., Silva, Jerson L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070981/ https://www.ncbi.nlm.nih.gov/pubmed/32085381 http://dx.doi.org/10.3390/molecules25040893

Ejemplares similares

Resveratrol prevents p53 aggregation in vitro and in breast cancer cells
por: Ferraz da Costa, Danielly C., et al.
Publicado: (2018)

Cancer Chemoprevention by Resveratrol: The p53 Tumor Suppressor Protein as a Promising Molecular Target
por: Ferraz da Costa, Danielly C., et al.
Publicado: (2017)

Anticancer Therapeutic Strategies Targeting p53 Aggregation
por: Ferretti, Giulia D. S., et al.
Publicado: (2022)

Characterization and trypanocidal activity of a β-lapachone-containing drug carrier
por: Barbosa, Juliana M. C., et al.
Publicado: (2021)

Bioactive Compounds and Metabolites from Grapes and Red Wine in Breast Cancer Chemoprevention and Therapy
por: Ferraz da Costa, Danielly C., et al.
Publicado: (2020)

In Silico Insights into the Mechanism of Action of Epoxy-α-Lapachone and Epoxymethyl-Lawsone in Leishmania spp.
por: Peixoto, Juliana Figueiredo, et al.
Publicado: (2021)

Transient Transfection of a Wild-Type p53 Gene Triggers Resveratrol-Induced Apoptosis in Cancer Cells
por: Ferraz da Costa, Danielly Cristiny, et al.
Publicado: (2012)

PRIMA-1 inhibits Y220C p53 amyloid aggregation and synergizes with cisplatin in hepatocellular carcinoma
por: Paz, Mariana M., et al.
Publicado: (2023)

Recent Synthetic Approaches towards Small Molecule Reactivators of p53
por: Silva, Jerson L., et al.
Publicado: (2020)

Machine intelligence decrypts β-lapachone as an allosteric 5-lipoxygenase inhibitor
por: Rodrigues, Tiago, et al.
Publicado: (2018)

The aggregation of mutant p53 produces prion-like properties in cancer
por: Rangel, Luciana P, et al.
Publicado: (2014)

First report of trans-A(2)B-corrole derived from a lapachone derivative: photophysical, TD-DFT and photobiological assays
por: Rodrigues, Bruna M., et al.
Publicado: (2023)

Unraveling the Anticancer Effect of Curcumin and Resveratrol
por: Pavan, Aline Renata, et al.
Publicado: (2016)

Efficient Catalytic Oxidation of 3-Arylthio- and 3-Cyclohexylthio-lapachone Derivatives to New Sulfonyl Derivatives and Evaluation of Their Antibacterial Activities
por: Cardoso, Mariana F. do C., et al.
Publicado: (2017)

Finding an efficient tetramethylated hydroxydiethylene of resveratrol analogue for potential anticancer agent
por: Xin, Zhen-Hui, et al.
Publicado: (2020)

Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer
por: de Oliveira, Guilherme A. P., et al.
Publicado: (2015)

Virtual Screening and Statistical Analysis in the Design of New Caffeine Analogues Molecules with Potential Epithelial Anticancer Activity
por: Costa, Josivan da Silva, et al.
Publicado: (2018)

ANTHELMINTIC ACTIVITY OF LAPACHOL, β-LAPACHONE AND ITS DERIVATIVES AGAINST Toxocara canis LARVAE
por: MATA-SANTOS, Taís, et al.
Publicado: (2015)

The combination therapy of meglumine antimoniate and oxiranes (epoxy-α-lapachone and epoxymethyl-lawsone) enhance the leishmanicidal effect in mice infected by Leishmania (Leishmania) amazonensis
por: Gonçalves-Oliveira, Luiz Filipe, et al.
Publicado: (2019)

Resveratrol effects in bladder cancer: A mini review
por: Almeida, Tamires Cunha, et al.
Publicado: (2021)

Resveratrol Modifies Lipid Composition of Two Cancer Cell Lines
por: Gomes, Luciana, et al.
Publicado: (2020)

Crystal Structure and Hydrogen Bonding Study of (10E)-2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione 10-Oxime Derived From α-Lapachone
por: da Silva, Andrea R., et al.
Publicado: (2011)

Expanding the prion concept to cancer biology: dominant-negative effect of aggregates of mutant p53 tumour suppressor
por: Silva, Jerson L., et al.
Publicado: (2013)

Green Tea (Camellia sinensis) Extract Induces p53-Mediated Cytotoxicity and Inhibits Migration of Breast Cancer Cells
por: Santos, Ronimara A., et al.
Publicado: (2021)

Loss of the p53 transactivation domain results in high amyloid aggregation of the Δ40p53 isoform in endometrial carcinoma cells
por: Melo dos Santos, Nataly, et al.
Publicado: (2019)

In vitro effects of lapachol and β-lapachone against Leishmania amazonensis
por: Ramos-Milaré, Á.C.F.H., et al.
Publicado: (2023)

Temperature-Sensitive Gels for Intratumoral Delivery of β-Lapachone: Effect of Cyclodextrins and Ethanol
por: Cunha-Filho, Marcilio S. S., et al.
Publicado: (2012)

Antimicrobial Activity of Resveratrol Analogues
por: Chalal, Malik, et al.
Publicado: (2014)

Naphth[1,2-d]imidazoles Bioactive from β-Lapachone: Fluorescent Probes and Cytotoxic Agents to Cancer Cells
por: Santos, Victória Laysna dos Anjos, et al.
Publicado: (2023)

The Role of Endophytic Fungi in the Anticancer Activity of Morinda citrifolia Linn. (Noni)
por: Wu, Yougen, et al.
Publicado: (2015)

The possibility of low isomerization of β-lapachone in the human body
por: Lee, Kyung Min, et al.
Publicado: (2021)

Phase 1 study of ARQ 761, a β-lapachone analogue that promotes NQO1-mediated programmed cancer cell necrosis
por: Gerber, David E., et al.
Publicado: (2018)

Resveratrol, Curcumin and Piperine Alter Human Glyoxalase 1 in MCF-7 Breast Cancer Cells
por: Schmidt, Betina, et al.
Publicado: (2020)

Increase in fatty acids and flotillins upon resveratrol treatment of human breast cancer cells
por: Gomes, Luciana, et al.
Publicado: (2019)

Anticancer Molecular Mechanisms of Resveratrol
por: Varoni, Elena M., et al.
Publicado: (2016)

Enhancement of radiation effect using beta-lapachone and underlying mechanism
por: Ahn, Ki Jung, et al.
Publicado: (2013)

Antibacterial and Antibiofilm Activities of β-Lapachone by Modulating the Catalase Enzyme
por: Mir, Mushtaq Ahmad, et al.
Publicado: (2023)

Unusual manifestation of fungal malignant external otitis
por: Ferreira, Mafalda da Silva, et al.
Publicado: (2020)

Controlled Release of Nor-β-lapachone by PLGA Microparticles: A Strategy for Improving Cytotoxicity against Prostate Cancer Cells
por: Costa, Marcilia P., et al.
Publicado: (2016)

Anticancer Compounds Based on Isatin-Derivatives: Strategies to Ameliorate Selectivity and Efficiency
por: Ferraz de Paiva, Raphael Enoque, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_n7lke4cv25mg7o02sl3ke2obs4