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Antibacterial Activity and Pharmacokinetic Profile of a Promising Antibacterial Agent: 22-(2-Amino-phenylsulfanyl)-22-Deoxypleuromutilin

A new pleuromutilin derivative, 22-(2-amino-phenylsulfanyl)-22-deoxypleuromutilin (amphenmulin), has been synthesized and proved excellent in vitro and in vivo efficacy than that of tiamulin against methicillin-resistant Staphylococcus aureus (MRSA), suggesting this compound may lead to a promising...

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Detalles Bibliográficos
Autores principales:	Zuo, Xiangyi, Fang, Xi, Zhang, Zhaosheng, Jin, Zhen, Xi, Gaolei, Liu, Yahong, Tang, Youzhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071076/ https://www.ncbi.nlm.nih.gov/pubmed/32079232 http://dx.doi.org/10.3390/molecules25040878

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