Cargando…
Characterising a Weight Loss Intervention in Obese Asthmatic Children
The prevalence of obesity in asthmatic children is high and is associated with worse clinical outcomes. We have previously reported that weight loss leads to improvements in lung function and asthma control in obese asthmatic children. The objectives of this secondary analysis were to examine: (1) c...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071161/ https://www.ncbi.nlm.nih.gov/pubmed/32079331 http://dx.doi.org/10.3390/nu12020507 |
_version_ | 1783506138153615360 |
---|---|
author | Eslick, Shaun Jensen, Megan E. Collins, Clare E. Gibson, Peter G. Hilton, Jodi Wood, Lisa G. |
author_facet | Eslick, Shaun Jensen, Megan E. Collins, Clare E. Gibson, Peter G. Hilton, Jodi Wood, Lisa G. |
author_sort | Eslick, Shaun |
collection | PubMed |
description | The prevalence of obesity in asthmatic children is high and is associated with worse clinical outcomes. We have previously reported that weight loss leads to improvements in lung function and asthma control in obese asthmatic children. The objectives of this secondary analysis were to examine: (1) changes in diet quality and (2) associations between the baseline subject characteristics and the degree of weight loss following the intervention. Twenty-eight obese asthmatic children, aged 8–17 years, completed a 10-week diet-induced weight loss intervention. Dietary intake, nutritional biomarkers, anthropometry, lung function, asthma control, and clinical outcomes were analysed before and after the intervention. Following the intervention, the body mass index (BMI) z-score decreased (Δ = 0.18 ± 0.04; p < 0.001), %energy from protein increased (Δ = 4.3 ± 0.9%; p = 0.002), and sugar intake decreased (Δ = 23.2 ± 9.3 g; p= 0.025). Baseline lung function and physical activity level were inversely associated with Δ% fat mass. The ΔBMI z-score was negatively associated with physical activity duration at baseline. Dietary intervention is effective in achieving acute weight loss in obese asthmatic children, with significant improvements in diet quality and body composition. Lower lung function and physical engagement at baseline were associated with lesser weight loss, highlighting that subjects with these attributes may require greater support to achieve weight loss goals. |
format | Online Article Text |
id | pubmed-7071161 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70711612020-03-19 Characterising a Weight Loss Intervention in Obese Asthmatic Children Eslick, Shaun Jensen, Megan E. Collins, Clare E. Gibson, Peter G. Hilton, Jodi Wood, Lisa G. Nutrients Article The prevalence of obesity in asthmatic children is high and is associated with worse clinical outcomes. We have previously reported that weight loss leads to improvements in lung function and asthma control in obese asthmatic children. The objectives of this secondary analysis were to examine: (1) changes in diet quality and (2) associations between the baseline subject characteristics and the degree of weight loss following the intervention. Twenty-eight obese asthmatic children, aged 8–17 years, completed a 10-week diet-induced weight loss intervention. Dietary intake, nutritional biomarkers, anthropometry, lung function, asthma control, and clinical outcomes were analysed before and after the intervention. Following the intervention, the body mass index (BMI) z-score decreased (Δ = 0.18 ± 0.04; p < 0.001), %energy from protein increased (Δ = 4.3 ± 0.9%; p = 0.002), and sugar intake decreased (Δ = 23.2 ± 9.3 g; p= 0.025). Baseline lung function and physical activity level were inversely associated with Δ% fat mass. The ΔBMI z-score was negatively associated with physical activity duration at baseline. Dietary intervention is effective in achieving acute weight loss in obese asthmatic children, with significant improvements in diet quality and body composition. Lower lung function and physical engagement at baseline were associated with lesser weight loss, highlighting that subjects with these attributes may require greater support to achieve weight loss goals. MDPI 2020-02-17 /pmc/articles/PMC7071161/ /pubmed/32079331 http://dx.doi.org/10.3390/nu12020507 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Eslick, Shaun Jensen, Megan E. Collins, Clare E. Gibson, Peter G. Hilton, Jodi Wood, Lisa G. Characterising a Weight Loss Intervention in Obese Asthmatic Children |
title | Characterising a Weight Loss Intervention in Obese Asthmatic Children |
title_full | Characterising a Weight Loss Intervention in Obese Asthmatic Children |
title_fullStr | Characterising a Weight Loss Intervention in Obese Asthmatic Children |
title_full_unstemmed | Characterising a Weight Loss Intervention in Obese Asthmatic Children |
title_short | Characterising a Weight Loss Intervention in Obese Asthmatic Children |
title_sort | characterising a weight loss intervention in obese asthmatic children |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071161/ https://www.ncbi.nlm.nih.gov/pubmed/32079331 http://dx.doi.org/10.3390/nu12020507 |
work_keys_str_mv | AT eslickshaun characterisingaweightlossinterventioninobeseasthmaticchildren AT jensenmegane characterisingaweightlossinterventioninobeseasthmaticchildren AT collinsclaree characterisingaweightlossinterventioninobeseasthmaticchildren AT gibsonpeterg characterisingaweightlossinterventioninobeseasthmaticchildren AT hiltonjodi characterisingaweightlossinterventioninobeseasthmaticchildren AT woodlisag characterisingaweightlossinterventioninobeseasthmaticchildren |