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Characterising a Weight Loss Intervention in Obese Asthmatic Children

The prevalence of obesity in asthmatic children is high and is associated with worse clinical outcomes. We have previously reported that weight loss leads to improvements in lung function and asthma control in obese asthmatic children. The objectives of this secondary analysis were to examine: (1) c...

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Autores principales: Eslick, Shaun, Jensen, Megan E., Collins, Clare E., Gibson, Peter G., Hilton, Jodi, Wood, Lisa G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071161/
https://www.ncbi.nlm.nih.gov/pubmed/32079331
http://dx.doi.org/10.3390/nu12020507
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author Eslick, Shaun
Jensen, Megan E.
Collins, Clare E.
Gibson, Peter G.
Hilton, Jodi
Wood, Lisa G.
author_facet Eslick, Shaun
Jensen, Megan E.
Collins, Clare E.
Gibson, Peter G.
Hilton, Jodi
Wood, Lisa G.
author_sort Eslick, Shaun
collection PubMed
description The prevalence of obesity in asthmatic children is high and is associated with worse clinical outcomes. We have previously reported that weight loss leads to improvements in lung function and asthma control in obese asthmatic children. The objectives of this secondary analysis were to examine: (1) changes in diet quality and (2) associations between the baseline subject characteristics and the degree of weight loss following the intervention. Twenty-eight obese asthmatic children, aged 8–17 years, completed a 10-week diet-induced weight loss intervention. Dietary intake, nutritional biomarkers, anthropometry, lung function, asthma control, and clinical outcomes were analysed before and after the intervention. Following the intervention, the body mass index (BMI) z-score decreased (Δ = 0.18 ± 0.04; p < 0.001), %energy from protein increased (Δ = 4.3 ± 0.9%; p = 0.002), and sugar intake decreased (Δ = 23.2 ± 9.3 g; p= 0.025). Baseline lung function and physical activity level were inversely associated with Δ% fat mass. The ΔBMI z-score was negatively associated with physical activity duration at baseline. Dietary intervention is effective in achieving acute weight loss in obese asthmatic children, with significant improvements in diet quality and body composition. Lower lung function and physical engagement at baseline were associated with lesser weight loss, highlighting that subjects with these attributes may require greater support to achieve weight loss goals.
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spelling pubmed-70711612020-03-19 Characterising a Weight Loss Intervention in Obese Asthmatic Children Eslick, Shaun Jensen, Megan E. Collins, Clare E. Gibson, Peter G. Hilton, Jodi Wood, Lisa G. Nutrients Article The prevalence of obesity in asthmatic children is high and is associated with worse clinical outcomes. We have previously reported that weight loss leads to improvements in lung function and asthma control in obese asthmatic children. The objectives of this secondary analysis were to examine: (1) changes in diet quality and (2) associations between the baseline subject characteristics and the degree of weight loss following the intervention. Twenty-eight obese asthmatic children, aged 8–17 years, completed a 10-week diet-induced weight loss intervention. Dietary intake, nutritional biomarkers, anthropometry, lung function, asthma control, and clinical outcomes were analysed before and after the intervention. Following the intervention, the body mass index (BMI) z-score decreased (Δ = 0.18 ± 0.04; p < 0.001), %energy from protein increased (Δ = 4.3 ± 0.9%; p = 0.002), and sugar intake decreased (Δ = 23.2 ± 9.3 g; p= 0.025). Baseline lung function and physical activity level were inversely associated with Δ% fat mass. The ΔBMI z-score was negatively associated with physical activity duration at baseline. Dietary intervention is effective in achieving acute weight loss in obese asthmatic children, with significant improvements in diet quality and body composition. Lower lung function and physical engagement at baseline were associated with lesser weight loss, highlighting that subjects with these attributes may require greater support to achieve weight loss goals. MDPI 2020-02-17 /pmc/articles/PMC7071161/ /pubmed/32079331 http://dx.doi.org/10.3390/nu12020507 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Eslick, Shaun
Jensen, Megan E.
Collins, Clare E.
Gibson, Peter G.
Hilton, Jodi
Wood, Lisa G.
Characterising a Weight Loss Intervention in Obese Asthmatic Children
title Characterising a Weight Loss Intervention in Obese Asthmatic Children
title_full Characterising a Weight Loss Intervention in Obese Asthmatic Children
title_fullStr Characterising a Weight Loss Intervention in Obese Asthmatic Children
title_full_unstemmed Characterising a Weight Loss Intervention in Obese Asthmatic Children
title_short Characterising a Weight Loss Intervention in Obese Asthmatic Children
title_sort characterising a weight loss intervention in obese asthmatic children
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071161/
https://www.ncbi.nlm.nih.gov/pubmed/32079331
http://dx.doi.org/10.3390/nu12020507
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