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5-Caffeoylquinic Acid Ameliorates Cognitive Decline and Reduces Aβ Deposition by Modulating Aβ Clearance Pathways in APP/PS2 Transgenic Mice

The accumulation of amyloid β (Aβ) in the brain is a major pathological feature of Alzheimer’s disease (AD). In our previous study, we demonstrated that coffee polyphenols (CPP) prevent cognitive dysfunction and Aβ deposition in the brain of an APP/PS2 transgenic mouse AD model. The underlying mecha...

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Detalles Bibliográficos
Autores principales:	Ishida, Keiko, Misawa, Koichi, Nishimura, Hitomi, Hirata, Tomoya, Yamamoto, Masaki, Ota, Noriyasu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071270/ https://www.ncbi.nlm.nih.gov/pubmed/32075202 http://dx.doi.org/10.3390/nu12020494

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