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Enhancing α-secretase Processing for Alzheimer’s Disease—A View on SFRP1
Amyloid β (Aβ) peptides generated via sequential β- and γ-secretase processing of the amyloid precursor protein (APP) are major etiopathological agents of Alzheimer’s disease (AD). However, an initial APP cleavage by an α-secretase, such as the a disintegrin and metalloproteinase domain-containing p...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071437/ https://www.ncbi.nlm.nih.gov/pubmed/32098349 http://dx.doi.org/10.3390/brainsci10020122 |