Cargando…

Lemur Tyrosine Kinase 2 (LMTK2) Level Inversely Correlates with Phospho-Tau in Neuropathological Stages of Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common neurodegenerative dementia. Mapping the pathomechanism and providing novel therapeutic options have paramount significance. Recent studies have proposed the role of LMTK2 in AD. However, its expression pattern and association with the pathognomonic neurofi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bencze, János, Szarka, Máté, Bencs, Viktor, Szabó, Renáta Nóra, Módis, László V., Aarsland, Dag, Hortobágyi, Tibor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071479/ https://www.ncbi.nlm.nih.gov/pubmed/32012723 http://dx.doi.org/10.3390/brainsci10020068

Ejemplares similares

Neuropathological characterization of Lemur tyrosine kinase 2 (LMTK2) in Alzheimer’s disease and neocortical Lewy body disease
por: Bencze, János, et al.
Publicado: (2019)

Biological function of Lemur tyrosine kinase 2 (LMTK2): implications in neurodegeneration
por: Bencze, János, et al.
Publicado: (2018)

Lemur tyrosine kinase-3 (LMTK3) in cancer and evolution
por: Stebbing, Justin, et al.
Publicado: (2011)

Comparison of Semi-Quantitative Scoring and Artificial Intelligence Aided Digital Image Analysis of Chromogenic Immunohistochemistry
por: Bencze, János, et al.
Publicado: (2021)

Lemur tyrosine kinase-3 (LMTK3) induces chemoresistance to cetuximab in colorectal cancer via the ERK/MAPK pathway
por: Wang, Cheng, et al.
Publicado: (2021)

Activation of TPA-response element present in human Lemur Tyrosine Kinase 2 (lmtk2) gene increases its expression
por: Dey, Isha, et al.
Publicado: (2017)

Extracellular matrix changes in corneal opacification vary depending on etiology
por: Módis, László V., et al.
Publicado: (2021)

Expression Pattern of Tenascin-C, Matrilin-2, and Aggrecan in Diseases Affecting the Corneal Endothelium
por: Varkoly, Gréta, et al.
Publicado: (2022)

Hippocampal phospho-tau/MAPT neuropathology in the fornix in Alzheimer disease: an immunohistochemical autopsy study
por: Plowey, Edward D., et al.
Publicado: (2016)

High Levels of β-Amyloid, Tau, and Phospho-Tau in Red Blood Cells as Biomarkers of Neuropathology in Senescence-Accelerated Mouse
por: Piccarducci, Rebecca, et al.
Publicado: (2019)

LMTK3 confers chemo-resistance in breast cancer
por: Stebbing, Justin, et al.
Publicado: (2018)

Unraveling the Function of Lemur Tyrosine Kinase 2 Network
por: Cruz, Daniel F., et al.
Publicado: (2019)

The structure-function relationship of oncogenic LMTK3
por: Ditsiou, Angeliki, et al.
Publicado: (2020)

LMTK3 inhibition affects microtubule stability
por: Cilibrasi, Chiara, et al.
Publicado: (2021)

Signal dependent ER export of lemur tyrosine kinase 2
por: Butler, E. C., et al.
Publicado: (2015)

The multifaceted role of lemur tyrosine kinase 3 in health and disease
por: Ditsiou, Angeliki, et al.
Publicado: (2021)

Lemur Tyrosine Kinases and Prostate Cancer: A Literature Review
por: Ferrari, Elena, et al.
Publicado: (2021)

Hyperactive and impulsive behaviors of LMTK1 knockout mice
por: Takahashi, Miyuki, et al.
Publicado: (2020)

Correction to: LMTK3 inhibition affects microtubule Stability
por: Cilibrasi, Chiara, et al.
Publicado: (2021)

Tyrosine Kinase Inhibitor Imatinib Mesylate Alters DMBA-Induced Early Onco/Suppressor Gene Expression with Tissue-Specificity in Mice
por: Gergely, Péter Attila, et al.
Publicado: (2019)

LMTK1, a Novel Modulator of Endosomal Trafficking in Neurons
por: Hisanaga, Shin-ichi, et al.
Publicado: (2020)

Distribution of caveolin isoforms in the lemur retina
por: Berta, Ágnes I, et al.
Publicado: (2007)

Characterization of Phospho-(Tyrosine)-Mimetic Calmodulin Mutants
por: Stateva, Silviya R., et al.
Publicado: (2015)

LMTK2 binds to kinesin light chains to mediate anterograde axonal transport of cdk5/p35 and LMTK2 levels are reduced in Alzheimer’s disease brains
por: Mórotz, Gábor M., et al.
Publicado: (2019)

Transcriptional Signatures of Tau and Amyloid Neuropathology
por: Castanho, Isabel, et al.
Publicado: (2020)

Lemur Tyrosine Kinase 2, a novel target in prostate cancer therapy
por: Shah, Kalpit, et al.
Publicado: (2015)

Toxoplasmosis in Captive Ring-Tailed Lemurs (Lemur catta)
por: Rocchigiani, Guido, et al.
Publicado: (2022)

The Inhibitory Properties of a Novel, Selective LMTK3 Kinase Inhibitor
por: Agnarelli, Alessandro, et al.
Publicado: (2023)

Numerical Rule-Learning in Ring-Tailed Lemurs (Lemur Catta)
por: Merritt, Dustin J., et al.
Publicado: (2011)

Assessing Allostatic Load in Ring-Tailed Lemurs (Lemur catta)
por: Seeley, Kathryn E., et al.
Publicado: (2021)

Phospho-tyrosine dependent protein–protein interaction network
por: Grossmann, Arndt, et al.
Publicado: (2015)

Apolipoprotein E decreases tau kinases and phospho-tau levels in primary neurons
por: Hoe, Hyang-Sook, et al.
Publicado: (2006)

Phospho-Tau and Cognitive Decline in Alzheimer's Disease. Commentary: Tau in physiology and pathology
por: DeFelipe, Javier
Publicado: (2016)

Phospho-Tau Bar Code: Analysis of Phosphoisotypes of Tau and Its Application to Tauopathy
por: Kimura, Taeko, et al.
Publicado: (2018)

Clinical value of neurofilament and phospho-tau/tau ratio in the frontotemporal dementia spectrum
por: Meeter, Lieke H.H., et al.
Publicado: (2018)

The study of Tau and phospho Tau protein levels in attention deficit and hyperactivity disorder
por: SARAÇOĞLU, Hatice, et al.
Publicado: (2021)

Saliva tau and phospho-tau-181 measured by Lumipulse in patients with Alzheimer’s disease
por: Marksteiner, Josef, et al.
Publicado: (2022)

LMTK3 is essential for oncogenic KIT expression in KIT-mutant GIST and melanoma
por: Klug, Lillian R., et al.
Publicado: (2018)

Molecular screening and docking analysis of LMTK3and AKT1 combined inhibitors
por: Allam, Loubna, et al.
Publicado: (2018)

CircLMTK2 acts as a novel tumor suppressor in gastric cancer
por: He, Jian, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_iiqh7mec95efmb7nq9dp2khoo4