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High-throughput quantitative histology in systemic sclerosis skin disease using computer vision

BACKGROUND: Skin fibrosis is the clinical hallmark of systemic sclerosis (SSc), where collagen deposition and remodeling of the dermis occur over time. The most widely used outcome measure in SSc clinical trials is the modified Rodnan skin score (mRSS), which is a semi-quantitative assessment of ski...

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Detalles Bibliográficos
Autores principales: Correia, Chase, Mawe, Seamus, Lofgren, Shane, Marangoni, Roberta G., Lee, Jungwha, Saber, Rana, Aren, Kathleen, Cheng, Michelle, Teaw, Shannon, Hoffmann, Aileen, Goldberg, Isaac, Cowper, Shawn E., Khatri, Purvesh, Hinchcliff, Monique, Mahoney, J. Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071594/
https://www.ncbi.nlm.nih.gov/pubmed/32171325
http://dx.doi.org/10.1186/s13075-020-2127-0