An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci

BACKGROUND: Previous studies using candidate gene and genome-wide approaches have identified epigenetic changes in DNA methylation (DNAm) associated with posttraumatic stress disorder (PTSD). METHODS: In this study, we performed an EWAS of PTSD in a cohort of Veterans (n = 378 lifetime PTSD cases an...

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Detalles Bibliográficos
Autores principales: Logue, Mark W., Miller, Mark W., Wolf, Erika J., Huber, Bertrand Russ, Morrison, Filomene G., Zhou, Zhenwei, Zheng, Yuanchao, Smith, Alicia K., Daskalakis, Nikolaos P., Ratanatharathorn, Andrew, Uddin, Monica, Nievergelt, Caroline M., Ashley-Koch, Allison E., Baker, Dewleen G., Beckham, Jean C., Garrett, Melanie E., Boks, Marco P., Geuze, Elbert, Grant, Gerald A., Hauser, Michael A., Kessler, Ronald C., Kimbrel, Nathan A., Maihofer, Adam X., Marx, Christine E., Qin, Xue-Jun, Risbrough, Victoria B., Rutten, Bart P. F., Stein, Murray B., Ursano, Robert J., Vermetten, Eric, Vinkers, Christiaan H., Ware, Erin B., Stone, Annjanette, Schichman, Steven A., McGlinchey, Regina E., Milberg, William P., Hayes, Jasmeet P., Verfaellie, Mieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071645/
https://www.ncbi.nlm.nih.gov/pubmed/32171335
http://dx.doi.org/10.1186/s13148-020-0820-0

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