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Specific humoral response in cancer patients treated with a VEGF-specific active immunotherapy procedure within a compassionate use program
BACKGROUND: CIGB-247 is a cancer therapeutic vaccine that uses as antigen a variant of human vascular endothelial growth factor (VEGF) mixed with the bacterially-derived adjuvant VSSP. CIGB-247 has been already evaluated in two phase I clinical trials (CENTAURO and CENTAURO-2), showing to be safe an...
Autores principales: | Sánchez Ramírez, Javier, Morera Díaz, Yanelys, Bequet-Romero, Mónica, Hernández-Bernal, Francisco, Martín Bauta, Yenima, Selman-Housein Bernal, Katty-Hind, de la Torre Santos, Ana Victoria, Pérez de la Iglesia, Mariela, Trimiño Lorenzo, Lian, Ayala Avila, Marta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071683/ https://www.ncbi.nlm.nih.gov/pubmed/32171254 http://dx.doi.org/10.1186/s12865-020-0338-4 |
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