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MicroRNA-495 confers inhibitory effects on cancer stem cells in oral squamous cell carcinoma through the HOXC6-mediated TGF-β signaling pathway

BACKGROUND: Oral squamous cell carcinoma (OSCC) is associated with high morbidity and ranks sixth among malignancies worldwide. Increasing evidence suggests that microRNAs (miRNAs or miRs) play a critical role in regulating cancer stem cells (CSCs), which drive the proliferation and spread of OSCC....

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Detalles Bibliográficos
Autores principales: You, Xiaolong, Zhou, Zhengyu, Chen, Wen, Wei, Xiaoyong, Zhou, Heqiang, Luo, Wenzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071696/
https://www.ncbi.nlm.nih.gov/pubmed/32171324
http://dx.doi.org/10.1186/s13287-020-1576-3