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Treating non-responders: pitfalls and implications for cancer immunotherapy trial design

BACKGROUND: Conventional trial design and analysis strategies fail to address the typical challenge of immune-oncology (IO) studies: only a limited percentage of treated patients respond to the experimental treatment. Treating non-responders, we hypothesize, would in part drive non-proportional haza...

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Detalles Bibliográficos
Autores principales:	Xu, Zhenzhen, Park, Yongsoek, Liu, Ke, Zhu, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071722/ https://www.ncbi.nlm.nih.gov/pubmed/32171307 http://dx.doi.org/10.1186/s13045-020-0847-x

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