Genotoxicity of cisplatin and carboplatin in cultured human lymphocytes: a comparative study

Cisplatin and carboplatin are integral parts of many antineoplastic management regimens. Both platinum analogues are potent DNA alkylating agents that robustly induce genomic instability and promote apoptosis in tumor cells. Although the mechanism of action of both drugs is similar, cisplatin appear...

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Detalles Bibliográficos
Autores principales: AZAB, Belal, ALASSAF, Anood, ABU-HUMDAN, Abdulrahman, DARDAS, Zain, ALMOUSA, Hashem, ALSALEM, Mohammad, KHABOUR, Omar, HAMMAD, Hana, SALEH, Tareq, AWIDI, Abdalla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071837/
https://www.ncbi.nlm.nih.gov/pubmed/32206030
http://dx.doi.org/10.2478/intox-2019-0011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071837/
https://www.ncbi.nlm.nih.gov/pubmed/32206030
http://dx.doi.org/10.2478/intox-2019-0011

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