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Genotoxicity of cisplatin and carboplatin in cultured human lymphocytes: a comparative study
Cisplatin and carboplatin are integral parts of many antineoplastic management regimens. Both platinum analogues are potent DNA alkylating agents that robustly induce genomic instability and promote apoptosis in tumor cells. Although the mechanism of action of both drugs is similar, cisplatin appear...
Autores principales: | AZAB, Belal, ALASSAF, Anood, ABU-HUMDAN, Abdulrahman, DARDAS, Zain, ALMOUSA, Hashem, ALSALEM, Mohammad, KHABOUR, Omar, HAMMAD, Hana, SALEH, Tareq, AWIDI, Abdalla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Slovak Toxicology Society SETOX
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071837/ https://www.ncbi.nlm.nih.gov/pubmed/32206030 http://dx.doi.org/10.2478/intox-2019-0011 |
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