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Alterations in chromatin at antigen receptor loci define lineage progression during B lymphopoiesis
Developing lymphocytes diversify their antigen receptor (AgR) loci by variable (diversity) joining (V[D]J) recombination. Here, using the micrococcal nuclease (MNase)-based chromatin accessibility (MACC) assay with low-cell count input, we profile both small-scale (kilobase) and large-scale (megabas...
Autores principales: | Lion, Mattia, Muhire, Brejnev, Namiki, Yuka, Tolstorukov, Michael Y., Oettinger, Marjorie A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071903/ https://www.ncbi.nlm.nih.gov/pubmed/32098847 http://dx.doi.org/10.1073/pnas.1914923117 |
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