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Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers

We sought to define the landscape of alternative pre-mRNA splicing in prostate cancers and the relationship of exon choice to known cancer driver alterations. To do so, we compiled a metadataset composed of 876 RNA-sequencing (RNA-Seq) samples from five publicly available sources representing a rang...

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Detalles Bibliográficos
Autores principales:	Phillips, John W., Pan, Yang, Tsai, Brandon L., Xie, Zhijie, Demirdjian, Levon, Xiao, Wen, Yang, Harry T., Zhang, Yida, Lin, Chia Ho, Cheng, Donghui, Hu, Qiang, Liu, Song, Black, Douglas L., Witte, Owen N., Xing, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2020
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071906/ https://www.ncbi.nlm.nih.gov/pubmed/32086391 http://dx.doi.org/10.1073/pnas.1915975117

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